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Novel interactions of fluorinated nucleotide derivatives targeting orotidine-5′-monophosphate decarboxylase

Fluorinated nucleosides and nucleotides are of considerable interest to medicinal chemists due to their antiviral, anticancer, and other biological activities. However, their direct interactions at target binding sites are not well understood. A new class of 2′-deoxy-2′-fluoro-C6-substituted uridine...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Lewis, Melissa, Avina, Maria Elena Meza, Wei, Lianhu, Crandall, Ian E., Bello, Angelica Mara, Poduch, Ewa, Liu, Yan, Paige, Christopher J., Kain, Kevin C., Pai, Emil F., Kotra, Lakshmi P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083246/
https://ncbi.nlm.nih.gov/pubmed/21417464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm101642g
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