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Novel interactions of fluorinated nucleotide derivatives targeting orotidine-5′-monophosphate decarboxylase
Fluorinated nucleosides and nucleotides are of considerable interest to medicinal chemists due to their antiviral, anticancer, and other biological activities. However, their direct interactions at target binding sites are not well understood. A new class of 2′-deoxy-2′-fluoro-C6-substituted uridine...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3083246/ https://ncbi.nlm.nih.gov/pubmed/21417464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm101642g |
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