Novel interactions of fluorinated nucleotide derivatives targeting orotidine-5′-monophosphate decarboxylase

Fluorinated nucleosides and nucleotides are of considerable interest to medicinal chemists due to their antiviral, anticancer, and other biological activities. However, their direct interactions at target binding sites are not well understood. A new class of 2′-deoxy-2′-fluoro-C6-substituted uridine...

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Detaylı Bibliyografya
Asıl Yazarlar: Lewis, Melissa, Avina, Maria Elena Meza, Wei, Lianhu, Crandall, Ian E., Bello, Angelica Mara, Poduch, Ewa, Liu, Yan, Paige, Christopher J., Kain, Kevin C., Pai, Emil F., Kotra, Lakshmi P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083246/
https://ncbi.nlm.nih.gov/pubmed/21417464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm101642g
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