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Novel interactions of fluorinated nucleotide derivatives targeting orotidine-5′-monophosphate decarboxylase

Fluorinated nucleosides and nucleotides are of considerable interest to medicinal chemists due to their antiviral, anticancer, and other biological activities. However, their direct interactions at target binding sites are not well understood. A new class of 2′-deoxy-2′-fluoro-C6-substituted uridine...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lewis, Melissa, Avina, Maria Elena Meza, Wei, Lianhu, Crandall, Ian E., Bello, Angelica Mara, Poduch, Ewa, Liu, Yan, Paige, Christopher J., Kain, Kevin C., Pai, Emil F., Kotra, Lakshmi P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083246/
https://ncbi.nlm.nih.gov/pubmed/21417464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm101642g
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