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Structural Determinants for Inhibitory Ligands of Orotidine-5′-Monophosphate Decarboxylase
In recent years, orotidine-5′-monophosphate decarboxylase (ODCase) has gained renewed attention as a drug target. As a part of continuing efforts to design novel inhibitors of ODCase, we undertook a comprehensive study of potent, structurally diverse ligands of ODCase and analyzed their structural i...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3124134/ https://ncbi.nlm.nih.gov/pubmed/20452222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.04.017 |
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