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Structural Determinants for Inhibitory Ligands of Orotidine-5′-Monophosphate Decarboxylase

In recent years, orotidine-5′-monophosphate decarboxylase (ODCase) has gained renewed attention as a drug target. As a part of continuing efforts to design novel inhibitors of ODCase, we undertook a comprehensive study of potent, structurally diverse ligands of ODCase and analyzed their structural i...

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Bibliografske podrobnosti
Main Authors: Meza-Avina, Maria Elena, Wei, Lianhu, Liu, Yan, Poduch, Ewa, Bello, Angelica M., Mishra, Ram K., Pai, Emil F., Kotra, Lakshmi P.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124134/
https://ncbi.nlm.nih.gov/pubmed/20452222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.04.017
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