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Mechanism of OMP Decarboxylation in Orotidine 5′-Monophosphate Decarboxylase

Despite extensive experimental and theoretical studies, the detailed catalytic mechanism of orotidine 5′-monophosphate decarboxylase (ODCase) remains controversial. In particular simulation studies using high level quantum mechanics have failed to reproduce experimental activation free energy. One c...

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Detalhes bibliográficos
Main Authors: Hu, Hao, Boone, Amy, Yang, Weitao
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651880/
https://ncbi.nlm.nih.gov/pubmed/18839943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja801202j
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