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Mechanism of OMP Decarboxylation in Orotidine 5′-Monophosphate Decarboxylase
Despite extensive experimental and theoretical studies, the detailed catalytic mechanism of orotidine 5′-monophosphate decarboxylase (ODCase) remains controversial. In particular simulation studies using high level quantum mechanics have failed to reproduce experimental activation free energy. One c...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3651880/ https://ncbi.nlm.nih.gov/pubmed/18839943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja801202j |
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