Novel interactions of fluorinated nucleotide derivatives targeting orotidine-5′-monophosphate decarboxylase

Fluorinated nucleosides and nucleotides are of considerable interest to medicinal chemists due to their antiviral, anticancer, and other biological activities. However, their direct interactions at target binding sites are not well understood. A new class of 2′-deoxy-2′-fluoro-C6-substituted uridine...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lewis, Melissa, Avina, Maria Elena Meza, Wei, Lianhu, Crandall, Ian E., Bello, Angelica Mara, Poduch, Ewa, Liu, Yan, Paige, Christopher J., Kain, Kevin C., Pai, Emil F., Kotra, Lakshmi P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083246/
https://ncbi.nlm.nih.gov/pubmed/21417464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm101642g
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