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Sugar binding induces the same global conformational change in purified LacY as in the native bacterial membrane

Many independent lines of evidence indicate that the lactose permease of Escherichia coli (LacY) is highly dynamic and that sugar binding causes closing of a large inward-facing cavity with opening of a wide outward-facing hydrophilic cavity. Therefore, lactose/H(+) symport catalyzed by LacY very li...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Nie, Yiling, Kaback, H. Ronald
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906848/
https://ncbi.nlm.nih.gov/pubmed/20457922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004515107
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