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Protonation and sugar binding to LacY

The effect of bulk-phase pH on the apparent affinity (K(d)(app)) of purified wild-type lactose permease (LacY) for sugars was studied. K(d)(app) values were determined by ligand-induced changes in the fluorescence of either of two covalently bound fluorescent reporters positioned away from the sugar...

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Detalhes bibliográficos
Main Authors: Smirnova, Irina N., Kasho, Vladimir, Kaback, H. Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021437/
https://ncbi.nlm.nih.gov/pubmed/18567672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803577105
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