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Sugar binding induces an outward facing conformation of LacY
According to x-ray structure, the lactose permease (LacY) is a monomer organized into N- and C-terminal six-helix bundles that form a deep internal cavity open on the cytoplasmic side with a single sugar-binding site at the apex. The periplasmic side of the molecule is closed. During sugar/H(+) symp...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2034228/ https://ncbi.nlm.nih.gov/pubmed/17925435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708258104 |
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