Ładuje się......
Targeting the protein prenyltransferases efficiently reduces tumor development in mice with K-RAS-induced lung cancer
RAS and RHO proteins, which contribute to tumorigenesis and metastasis, undergo posttranslational modification with an isoprenyl lipid by protein farnesyltransferase (FTase) or protein geranylgeranyltransferase-I (GGTase-I). Inhibitors of FTase and GGTase-I were developed to block RAS-induced malign...
Zapisane w:
| Główni autorzy: | , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2010
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852017/ https://ncbi.nlm.nih.gov/pubmed/20308544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908396107 |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|