Targeting filamin A reduces K-RAS–induced lung adenocarcinomas and endothelial response to tumor growth in mice

BACKGROUND: Many human cancer cells express filamin A (FLNA), an actin-binding structural protein that interacts with a diverse set of cell signaling proteins, but little is known about the biological importance of FLNA in tumor development. FLNA is also expressed in endothelial cells, which may be...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Nallapalli, Rajesh K, Ibrahim, Mohamed X, Zhou, Alex X, Bandaru, Sashidar, Sunkara, Sai Naresh, Redfors, Björn, Pazooki, David, Zhang, Yin, Borén, Jan, Cao, Yihai, Bergo, Martin O, Akyürek, Levent M
التنسيق: Artigo
اللغة:Inglês
منشور في: BioMed Central 2012
الموضوعات:
Research
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441416/
https://ncbi.nlm.nih.gov/pubmed/22857000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-50
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