Thyrotropin (TSH) Receptor Residue E251 in the Extracellular Leucine-Rich Repeat Domain Is Critical for Linking TSH Binding to Receptor Activation

Antzeko izenburuak

• A Monoclonal Antibody with Thyrotropin (TSH) Receptor Inverse Agonist and TSH Antagonist Activities Binds to the Receptor Hinge Region as Well as to the Leucine-Rich Domain
  nork: Chen, Chun-Rong, et al.
  Argitaratua: (2009)
• The Thyrotropin Receptor Hinge Region Is Not Simply a Scaffold for the Leucine-Rich Domain but Contributes to Ligand Binding and Signal Transduction
  nork: Mizutori, Yumiko, et al.
  Argitaratua: (2008)
• Evidence That the Thyroid-stimulating Hormone (TSH) Receptor Transmembrane Domain Influences Kinetics of TSH Binding to the Receptor Ectodomain
  nork: Chen, Chun-Rong, et al.
  Argitaratua: (2011)
• Identification of Key Amino Acid Residues in a Thyrotropin Receptor Monoclonal Antibody Epitope Provides Insight into Its Inverse Agonist and Antagonist Properties
  nork: Chen, Chun-Rong, et al.
  Argitaratua: (2008)
• Deleting the Redundant TSH Receptor C-Peptide Region Permits Generation of the Conformationally Intact Extracellular Domain by Insect Cells
  nork: Chen, Chun-Rong, et al.
  Argitaratua: (2015)