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Initial Testing of Aplidin by the Pediatric Preclinical Testing Program
Aplidin was tested in vitro at concentrations ranging from from 0.1 nM to 1.0 μM and in vivo at a dose of 0.6 mg/kg administered intraperitoneally on an every 4 days × 3 schedule that was repeated at day 21. In vitro, Aplidin was most active against acute lymphoblastic leukemia (ALL) cell lines. In...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777698/ https://ncbi.nlm.nih.gov/pubmed/19418543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.21976 |
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