Initial Testing of Aplidin by the Pediatric Preclinical Testing Program

Aplidin was tested in vitro at concentrations ranging from from 0.1 nM to 1.0 μM and in vivo at a dose of 0.6 mg/kg administered intraperitoneally on an every 4 days × 3 schedule that was repeated at day 21. In vitro, Aplidin was most active against acute lymphoblastic leukemia (ALL) cell lines. In...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Morton, Christopher L., Houghton, Peter J., Gorlick, Richard, Kolb, E. Anders, Lock, Richard, Carol, Hernan, Keir, Stephen T., Reynolds, C. Patrick, Kang, Min H., Maris, John M., Billups, Catherine, Smith, Malcolm A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777698/
https://ncbi.nlm.nih.gov/pubmed/19418543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.21976
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