Lataa...
Initial Testing (Stage 1) of LCL161, a SMAC Mimetic, by the Pediatric Preclinical Testing Program
LCL161, a SMAC mimetic, was tested against the PPTP in vitro panel (1.0 nM to 10.0 μM) and the PPTP in vivo panels (30 mg/kg or 75 mg/kg [solid tumors] or 100 mg/kg [ALL]) administered orally twice weekly. LCL161 showed a median relative IC(50) value of >10 μM, being more potent against several l...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2011
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253328/ https://ncbi.nlm.nih.gov/pubmed/21681929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.23167 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|