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WRN exonuclease activity is blocked by DNA termini harboring 3' obstructive groups
Reactive oxygen species, generated either by cellular respiration or upon exposure to environmental agents such as ionizing radiation (IR), attack DNA to form a variety of oxidized base and sugar modifications. Accumulation of oxidative DNA damage has been associated with age-related disease as well...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1920796/ https://ncbi.nlm.nih.gov/pubmed/17224176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2006.12.005 |
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