WRN exonuclease activity is blocked by DNA termini harboring 3' obstructive groups

Reactive oxygen species, generated either by cellular respiration or upon exposure to environmental agents such as ionizing radiation (IR), attack DNA to form a variety of oxidized base and sugar modifications. Accumulation of oxidative DNA damage has been associated with age-related disease as well...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Harrigan, Jeanine A., Fan, Jinshui, Momand, Jamil, Perrino, Fred W., Bohr, Vilhelm A., Wilson, David M.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920796/
https://ncbi.nlm.nih.gov/pubmed/17224176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2006.12.005
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki