WRN exonuclease activity is blocked by DNA termini harboring 3' obstructive groups

Reactive oxygen species, generated either by cellular respiration or upon exposure to environmental agents such as ionizing radiation (IR), attack DNA to form a variety of oxidized base and sugar modifications. Accumulation of oxidative DNA damage has been associated with age-related disease as well...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Harrigan, Jeanine A., Fan, Jinshui, Momand, Jamil, Perrino, Fred W., Bohr, Vilhelm A., Wilson, David M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2006
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920796/
https://ncbi.nlm.nih.gov/pubmed/17224176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2006.12.005
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak