Selective blockage of the 3′→5′ exonuclease activity of WRN protein by certain oxidative modifications and bulky lesions in DNA

Lignende værker

• WRN Exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand
  af: Bukowy, Zuzanna, et al.
  Udgivet: (2008)
• The DNA structure and sequence preferences of WRN underlie its function in telomeric recombination events
  af: Edwards, Deanna N., et al.
  Udgivet: (2015)
• Replication fork regression in vitro by the Werner syndrome protein (WRN): Holliday junction formation, the effect of leading arm structure and a potential role for WRN exonuclease activity
  af: Machwe, Amrita, et al.
  Udgivet: (2007)
• DNA secondary structure of the released strand stimulates WRN helicase action on forked duplexes without coordinate action of WRN exonuclease
  af: Ahn, Byungchan, et al.
  Udgivet: (2011)
• Length-dependent degradation of single-stranded 3' ends by the Werner syndrome protein (WRN): implications for spatial orientation and coordinated 3' to 5' movement of its ATPase/helicase and exonuclease domains
  af: Machwe, Amrita, et al.
  Udgivet: (2006)