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Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells

Triptolide, a diterpenoid isolated from the Chinese herb Tripterygium wilfordii Hook.f, has shown antitumor activities in a broad range of solid tumors. Here, we examined its effects on leukemic cells and found that, at 100 nM or less, it potently induced apoptosis in various leukemic cell lines and...

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Detaylı Bibliyografya
Asıl Yazarlar: Carter, Bing Z., Mak, Duncan H., Schober, Wendy D., McQueen, Teresa, Harris, David, Estrov, Zeev, Evans, Randall L., Andreeff, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society of Hematology 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895484/
https://ncbi.nlm.nih.gov/pubmed/16556893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-09-3898
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