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Double-stranded regions are essential design components of potent inhibitors of RISC function
While microRNAs (miRNAs) are recognized as playing a critical role in regulating eukaryotic gene expression, both the mechanism by which these small, noncoding RNAs function and the genes they target remain elusive. Previous studies have shown that short, single-stranded 2′-O-methyl-modified oligonu...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Cold Spring Harbor Laboratory Press
2007
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852807/ https://ncbi.nlm.nih.gov/pubmed/17400817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.448107 |
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