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Double-stranded regions are essential design components of potent inhibitors of RISC function

While microRNAs (miRNAs) are recognized as playing a critical role in regulating eukaryotic gene expression, both the mechanism by which these small, noncoding RNAs function and the genes they target remain elusive. Previous studies have shown that short, single-stranded 2′-O-methyl-modified oligonu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Vermeulen, Annaleen, Robertson, Barbara, Dalby, Andrew B., Marshall, William S., Karpilow, Jon, Leake, Devin, Khvorova, Anastasia, Baskerville, Scott
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852807/
https://ncbi.nlm.nih.gov/pubmed/17400817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.448107
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