Crystal structure of human stem cell factor: Implication for stem cell factor receptor dimerization and activation
Stem cell factor (SCF) plays important roles in hematopoiesis and the survival, proliferation, and differentiation of mast cells, melanocytes, and germ cells. SCF mediates its biological effects by binding to and activating a receptor tyrosine kinase designated c-kit or SCF receptor. In this report...
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| Опубліковано в:: | Proc Natl Acad Sci U S A |
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| Автори: | , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
National Academy of Sciences
2000
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16613/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10884405/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.14.7732 |
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