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Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat.

We investigated whether platelet-derived growth factor (PDGF), or its receptor (PDGF-R), was upregulated in a rat model of mesangial proliferative glomerulonephritis. A marked increase in both PDGF A- and B-chain mRNA could be demonstrated in glomerular RNA by Northern blot analysis 3 and 5 days aft...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Iida, H, Seifert, R, Alpers, C E, Gronwald, R G, Phillips, P E, Pritzl, P, Gordon, K, Gown, A M, Ross, R, Bowen-Pope, D F
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52126/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1713682/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.15.6560
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