Crystal structure of human stem cell factor: Implication for stem cell factor receptor dimerization and activation

Stem cell factor (SCF) plays important roles in hematopoiesis and the survival, proliferation, and differentiation of mast cells, melanocytes, and germ cells. SCF mediates its biological effects by binding to and activating a receptor tyrosine kinase designated c-kit or SCF receptor. In this report...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Zhang, Zhongtao, Zhang, Rongguang, Joachimiak, Andrzej, Schlessinger, Joseph, Kong, Xiang-Peng
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 2000
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16613/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10884405/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.14.7732
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