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Neurotrophic activity of platelet-derived growth factor (PDGF): Rat neuronal cells possess functional PDGF beta-type receptors and respond to PDGF.

The different isoforms of PDGF bind with different affinities to two different receptor types. Previously, these receptors have been demonstrated mainly on mesenchymal and glial cells. We show here that PDGF beta-type receptors are present also on rat brain neurons in vivo as well as in vitro. Immun...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Smits, A, Kato, M, Westermark, B, Nistér, M, Heldin, C H, Funa, K
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1991
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52466/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1654560/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.18.8159
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