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Platelet-derived growth factor (PDGF) in oncogenesis: development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB.

Human WM9 melanoma cells, previously shown to be devoid of PDGF expression, were stably transfected with a PDGF-B cDNA under the transcriptional control of a cytomegalovirus promoter. Northern blot analysis revealed high expression of an mRNA of the expected size in the PDGF-B-transfected cells. Syn...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Forsberg, K, Valyi-Nagy, I, Heldin, C H, Herlyn, M, Westermark, B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45668/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8380638/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.2.393
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