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Crystal structure of human stem cell factor: Implication for stem cell factor receptor dimerization and activation

Stem cell factor (SCF) plays important roles in hematopoiesis and the survival, proliferation, and differentiation of mast cells, melanocytes, and germ cells. SCF mediates its biological effects by binding to and activating a receptor tyrosine kinase designated c-kit or SCF receptor. In this report...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Zhang, Zhongtao, Zhang, Rongguang, Joachimiak, Andrzej, Schlessinger, Joseph, Kong, Xiang-Peng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2000
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16613/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10884405/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.14.7732
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