Crystal structure of human stem cell factor: Implication for stem cell factor receptor dimerization and activation

Stem cell factor (SCF) plays important roles in hematopoiesis and the survival, proliferation, and differentiation of mast cells, melanocytes, and germ cells. SCF mediates its biological effects by binding to and activating a receptor tyrosine kinase designated c-kit or SCF receptor. In this report...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Zhang, Zhongtao, Zhang, Rongguang, Joachimiak, Andrzej, Schlessinger, Joseph, Kong, Xiang-Peng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16613/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10884405/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.14.7732
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