Platelet-derived growth factor (PDGF) binding promotes physical association of PDGF receptor with phospholipase C.

Phospholipase C (PLC)-mediated production of inositol trisphosphate and diacylglycerol is stimulated by binding of platelet-derived growth factor (PDGF) to cell-surface receptors. Antibodies recognizing native PDGF receptors through peptide-domain epitopes coprecipitated 4-fold more PLC activity wit...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kumjian, D A, Wahl, M I, Rhee, S G, Daniel, T O
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298254/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2554305/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.21.8232
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