Platelet-derived growth factor (PDGF) binding promotes physical association of PDGF receptor with phospholipase C.

Phospholipase C (PLC)-mediated production of inositol trisphosphate and diacylglycerol is stimulated by binding of platelet-derived growth factor (PDGF) to cell-surface receptors. Antibodies recognizing native PDGF receptors through peptide-domain epitopes coprecipitated 4-fold more PLC activity wit...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Kumjian, D A, Wahl, M I, Rhee, S G, Daniel, T O
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1989
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC298254/
https://ncbi.nlm.nih.gov/pubmed/2554305
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