Platelet-derived growth factor (PDGF) binding promotes physical association of PDGF receptor with phospholipase C.
Phospholipase C (PLC)-mediated production of inositol trisphosphate and diacylglycerol is stimulated by binding of platelet-derived growth factor (PDGF) to cell-surface receptors. Antibodies recognizing native PDGF receptors through peptide-domain epitopes coprecipitated 4-fold more PLC activity wit...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1989
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298254/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2554305/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.21.8232 |
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