Crystal structure of human stem cell factor: Implication for stem cell factor receptor dimerization and activation

Stem cell factor (SCF) plays important roles in hematopoiesis and the survival, proliferation, and differentiation of mast cells, melanocytes, and germ cells. SCF mediates its biological effects by binding to and activating a receptor tyrosine kinase designated c-kit or SCF receptor. In this report...

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Bibliografiset tiedot

Julkaisussa:	Proc Natl Acad Sci U S A
Päätekijät:	Zhang, Zhongtao, Zhang, Rongguang, Joachimiak, Andrzej, Schlessinger, Joseph, Kong, Xiang-Peng
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	National Academy of Sciences 2000
Aiheet:	Biological Sciences
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16613/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10884405/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.14.7732
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