Antifungal Activity of Eupolauridine and Its Action on DNA Topoisomerases

The azafluoranthene alkaloid eupolauridine has previously been shown to have in vitro antifungal activity and selective inhibition of fungal topoisomerase I. The present study was undertaken to examine further its selectivity and mode of action. Eupolauridine completely inhibits the DNA relaxation a...

Celý popis

Podrobná bibliografie

Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Khan, Shabana I., Nimrod, Alison C., Mehrpooya, Mohammed, Nitiss, John L., Walker, Larry A., Clark, Alice M.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2002
Témata:	Mechanisms of Action: Physiological Effects
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127229/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019091/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.1785-1792.2002
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!