Antifungal Activity of Eupolauridine and Its Action on DNA Topoisomerases

The azafluoranthene alkaloid eupolauridine has previously been shown to have in vitro antifungal activity and selective inhibition of fungal topoisomerase I. The present study was undertaken to examine further its selectivity and mode of action. Eupolauridine completely inhibits the DNA relaxation a...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Khan, Shabana I., Nimrod, Alison C., Mehrpooya, Mohammed, Nitiss, John L., Walker, Larry A., Clark, Alice M.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2002
Matèries:	Mechanisms of Action: Physiological Effects
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127229/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019091/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.1785-1792.2002
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