Antifungal Activity of Eupolauridine and Its Action on DNA Topoisomerases

The azafluoranthene alkaloid eupolauridine has previously been shown to have in vitro antifungal activity and selective inhibition of fungal topoisomerase I. The present study was undertaken to examine further its selectivity and mode of action. Eupolauridine completely inhibits the DNA relaxation a...

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Argitaratua izan da:	Antimicrob Agents Chemother
Egile Nagusiak:	Khan, Shabana I., Nimrod, Alison C., Mehrpooya, Mohammed, Nitiss, John L., Walker, Larry A., Clark, Alice M.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 2002
Gaiak:	Mechanisms of Action: Physiological Effects
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127229/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019091/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.1785-1792.2002
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