Antifungal Activity of Eupolauridine and Its Action on DNA Topoisomerases

The azafluoranthene alkaloid eupolauridine has previously been shown to have in vitro antifungal activity and selective inhibition of fungal topoisomerase I. The present study was undertaken to examine further its selectivity and mode of action. Eupolauridine completely inhibits the DNA relaxation a...

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Opis bibliograficzny

Wydane w:	Antimicrob Agents Chemother
Główni autorzy:	Khan, Shabana I., Nimrod, Alison C., Mehrpooya, Mohammed, Nitiss, John L., Walker, Larry A., Clark, Alice M.
Format:	Artigo
Język:	Inglês
Wydane:	American Society for Microbiology (ASM) 2002
Hasła przedmiotowe:	Mechanisms of Action: Physiological Effects
Dostęp online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127229/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019091/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.1785-1792.2002
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