CAR Gene Delivery by T‐cell Targeted Lentiviral Vectors is Enhanced by Rapamycin Induced Reduction of Antiviral Mechanisms

Abstract Lentiviral vectors (LV) have become the dominant tool for stable gene transfer into lymphocytes including chimeric antigen receptor (CAR) gene delivery to T cells, a major breakthrough in cancer therapy. Yet, room for improvement remains, especially for the latest LV generations delivering...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Filippos T Charitidis, Elham Adabi, Naphang Ho, Angela H Braun, Ciara Tierney, Lisa Strasser, Frederic B Thalheimer, Liam Childs, Jonathan Bones, Colin Clarke, Christian J Buchholz
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Wiley 2023-12-01
Reeks:	Advanced Science
Onderwerpen:	CAR T cells IFITM in vivo gene delivery rapamycin receptor‐targeted vectors transduction enhancer
Online toegang:	https://doi.org/10.1002/advs.202302992
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!