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Enhanced conversion of T cells into CAR T cells by modulation of the MAPK/ERK pathway

Summary: Delivery of chimeric antigen receptors (CARs) to T cells is usually mediated by lentiviral vectors (LVs), which can have broad tropism or be T cell targeted. To better understand the molecular events during CAR T cell generation, T cell transduction with four different LVs is followed by si...

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Detaylı Bibliyografya
Asıl Yazarlar: Elham Adabi, Filippos T. Charitidis, Frederic B. Thalheimer, Mar Guaza-Lasheras, Colin Clarke, Christian J. Buchholz
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2025-02-01
Seri Bilgileri:Cell Reports Medicine
Konular:
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2666379125000436
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