CAR Gene Delivery by T‐cell Targeted Lentiviral Vectors is Enhanced by Rapamycin Induced Reduction of Antiviral Mechanisms

Abstract Lentiviral vectors (LV) have become the dominant tool for stable gene transfer into lymphocytes including chimeric antigen receptor (CAR) gene delivery to T cells, a major breakthrough in cancer therapy. Yet, room for improvement remains, especially for the latest LV generations delivering...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Filippos T Charitidis, Elham Adabi, Naphang Ho, Angela H Braun, Ciara Tierney, Lisa Strasser, Frederic B Thalheimer, Liam Childs, Jonathan Bones, Colin Clarke, Christian J Buchholz
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Wiley 2023-12-01
سلاسل:	Advanced Science
الموضوعات:	CAR T cells IFITM in vivo gene delivery rapamycin receptor‐targeted vectors transduction enhancer
الوصول للمادة أونلاين:	https://doi.org/10.1002/advs.202302992
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!