Shutting down the power supply for DNA repair in cancer cells

Por van Vugt, Marcel A.T.M.
Publicado no J Cell Biol (2017)

Editorial: Cancer-Associated Defects in the DNA Damage Response: Drivers for Malignant Transformation and Potential Therapeutic Targets

Por van Vugt, Marcel A. T. M., Reinhardt, H. Christian
Publicado no Front Genet (2015)

Never tear us a-PARP: Dealing with DNA lesions during mitosis

Por Schoonen, Pepijn M., van Vugt, Marcel A.T.M.
Publicado no Mol Cell Oncol (2017)

Controlling the response to DNA damage by the APC/C-Cdh1

Por de Boer, H. Rudolf, Guerrero Llobet, S., van Vugt, Marcel A. T. M.
Publicado no Cell Mol Life Sci (2015)

Erratum to: Controlling the response to DNA damage by the APC/C-Cdh1

Por de Boer, H. Rudolf, Llobet, Sergi Guerrero, van Vugt, Marcel A. T. M.
Publicado no Cell Mol Life Sci (2016)

CLIP-170 facilitates the formation of kinetochore–microtubule attachments

Por Tanenbaum, Marvin E, Galjart, Niels, van Vugt, Marcel A T M, Medema, René H
Publicado em 2006

Functional Dynamics of Polo-Like Kinase 1 at the Centrosome

Por Kishi, Kazuhiro, van Vugt, Marcel A. T. M., Okamoto, Ken-ichi, Hayashi, Yasunori, Yaffe, Michael B.
Publicado em 2009

Regulators of homologous recombination repair as novel targets for cancer treatment

Por Krajewska, Małgorzata, Fehrmann, Rudolf S. N., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M.
Publicado no Front Genet (2015)

Harnessing Integrative Omics to Facilitate Molecular Imaging of the Human Epidermal Growth Factor Receptor Family for Precision Medicine

Por Pool, Martin, de Boer, H. Rudolf, Hooge, Marjolijn N. Lub-de, van Vugt, Marcel A.T.M., de Vries, Elisabeth G.E.
Publicado no Theranostics (2017)

A haploid genetic screen identifies the G(1)/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity

Por Heijink, Anne Margriet, Blomen, Vincent A., Bisteau, Xavier, Degener, Fabian, Matsushita, Felipe Yu, Kaldis, Philipp, Foijer, Floris, van Vugt, Marcel A. T. M.
Publicado no Proc Natl Acad Sci U S A (2015)

BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity

Por Heijink, Anne Margriet, Talens, Francien, Jae, Lucas T., van Gijn, Stephanie E., Fehrmann, Rudolf S. N., Brummelkamp, Thijn R., van Vugt, Marcel A. T. M.
Publicado no Nat Commun (2019)

Functional validation of putative tumor suppressor gene C13ORF18 in cervical cancer by Artificial Transcription Factors

Por Huisman, Christian, Wisman, G. Bea A., Kazemier, Hinke G., van Vugt, Marcel A.T.M., van der Zee, Ate G.J., Schuuring, Ed, Rots, Marianne G.
Publicado no Mol Oncol (2013)

Polo-Like Kinase-1 Controls Aurora A Destruction by Activating APC/C-Cdh1

Por van Leuken, Renske, Clijsters, Linda, van Zon, Wouter, Lim, Dan, Yao, XueBiao, Wolthuis, Rob M. F., Yaffe, Michael B., Medema, René H., van Vugt, Marcel A. T. M.
Publicado em 2009

Uncoupling Anaphase-Promoting Complex/Cyclosome Activity from Spindle Assembly Checkpoint Control by Deregulating Polo-Like Kinase 1

Por van de Weerdt, Barbara C. M., van Vugt, Marcel A. T. M., Lindon, Catherine, Kauw, Jos J. W., Rozendaal, Marieke J., Klompmaker, Rob, Wolthuis, Rob M. F., Medema, René H.
Publicado em 2005

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells

Por Schoonen, Pepijn M., Talens, Francien, Stok, Colin, Gogola, Ewa, Heijink, Anne Margriet, Bouwman, Peter, Foijer, Floris, Tarsounas, Madalena, Blatter, Sohvi, Jonkers, Jos, Rottenberg, Sven, van Vugt, Marcel A. T. M.
Publicado no Nat Commun (2017)

DNA Damage activates A Spatially Distinct Late Cytoplasmic Cell Cycle Checkpoint Network Controlled by MK2-mediated RNA Stabilization

Por Reinhardt, H. Christian, Hasskamp, Pia, Schmedding, Ingolf, Morandell, Sandra, van Vugt, Marcel .A.T.M., Wang, XiaoZhe, Linding, Rune, Ong, Shao-En, Weaver, David, Carr, Steven A., Yaffe, Michael B.
Publicado em 2010

Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer

Por Bense, Rico D., Sotiriou, Christos, Piccart-Gebhart, Martine J., Haanen, John B. A. G., van Vugt, Marcel A. T. M., de Vries, Elisabeth G. E., Schröder, Carolien P., Fehrmann, Rudolf S. N.
Publicado no J Natl Cancer Inst (2016)

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells

Por van Gijn, Stephanie E., Wierenga, Elles, van den Tempel, Nathalie, Kok, Yannick P., Heijink, Anne Margriet, Spierings, Diana C. J., Foijer, Floris, van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.
Publicado no Oncogene (2018)

Nuclear COMMD1 Is Associated with Cisplatin Sensitivity in Ovarian Cancer

Por Fedoseienko, Alina, Wieringa, Hylke W., Wisman, G. Bea A., Duiker, Evelien, Reyners, Anna K. L., Hofker, Marten H., van der Zee, Ate G. J., van de Sluis, Bart, van Vugt, Marcel A. T. M.
Publicado no PLoS One (2016)

PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy

Por Ruf, Stefanie, Heberle, Alexander Martin, Langelaar-Makkinje, Miriam, Gelino, Sara, Wilkinson, Deepti, Gerbeth, Carolin, Schwarz, Jennifer Jasmin, Holzwarth, Birgit, Warscheid, Bettina, Meisinger, Chris, van Vugt, Marcel A. T. M., Baumeister, Ralf, Hansen, Malene, Thedieck, Kathrin
Publicado no Autophagy (2017)