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Functional Dynamics of Polo-Like Kinase 1 at the Centrosome

Polo-like kinase 1 (Plk1) functions as a key regulator of mitotic events by phosphorylating substrate proteins on centrosomes, kinetochores, the mitotic spindle, and the midbody. Through mechanisms that are incompletely understood, Plk1 is released from and relocalizes to different mitotic structure...

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Detalhes bibliográficos
Main Authors: Kishi, Kazuhiro, van Vugt, Marcel A. T. M., Okamoto, Ken-ichi, Hayashi, Yasunori, Yaffe, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682011/
https://ncbi.nlm.nih.gov/pubmed/19307309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01663-08
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