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Functional Dynamics of Polo-Like Kinase 1 at the Centrosome

Polo-like kinase 1 (Plk1) functions as a key regulator of mitotic events by phosphorylating substrate proteins on centrosomes, kinetochores, the mitotic spindle, and the midbody. Through mechanisms that are incompletely understood, Plk1 is released from and relocalizes to different mitotic structure...

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Bibliografiska uppgifter
Huvudupphovsmän: Kishi, Kazuhiro, van Vugt, Marcel A. T. M., Okamoto, Ken-ichi, Hayashi, Yasunori, Yaffe, Michael B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682011/
https://ncbi.nlm.nih.gov/pubmed/19307309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01663-08
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