Gene duplications resulting in over expression of glucokinase are not a common cause of hypoglycaemia of infancy in humans

অনুযায়ী van de Bunt, Martijn, Edghill, Emma L., Hussain, Khalid, Ellard, Sian, Gloyn, Anna L.
প্রকাশিত 2008

A Multi-tissue Transcriptome Analysis of Human Metabolites Guides Interpretability of Associations Based on Multi-SNP Models for Gene Expression

অনুযায়ী Ndungu, Anne, Payne, Anthony, Torres, Jason M., van de Bunt, Martijn, McCarthy, Mark I.
প্রকাশিত Am J Hum Genet (2020)

Evaluating the Performance of Fine-Mapping Strategies at Common Variant GWAS Loci

অনুযায়ী van de Bunt, Martijn, Cortes, Adrian, Brown, Matthew A., Morris, Andrew P., McCarthy, Mark I.
প্রকাশিত PLoS Genet (2015)

SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells

অনুযায়ী Kailey, Balrik, van de Bunt, Martijn, Cheley, Stephen, Johnson, Paul R., MacDonald, Patrick E., Gloyn, Anna L., Rorsman, Patrik, Braun, Matthias
প্রকাশিত 2012

Insights into islet development and biology through characterization of a human iPSC-derived endocrine pancreas model

অনুযায়ী van de Bunt, Martijn, Lako, Majlinda, Barrett, Amy, Gloyn, Anna L., Hansson, Mattias, McCarthy, Mark I., Beer, Nicola L., Honoré, Christian
প্রকাশিত Islets (2016)

Discovery of a Novel Site Regulating Glucokinase Activity following Characterization of a New Mutation Causing Hyperinsulinemic Hypoglycemia in Humans

অনুযায়ী Beer, Nicola L., van de Bunt, Martijn, Colclough, Kevin, Lukacs, Christine, Arundel, Paul, Chik, Constance L., Grimsby, Joseph, Ellard, Sian, Gloyn, Anna L.
প্রকাশিত 2011

Systematic Functional Characterization of Candidate Causal Genes for Type 2 Diabetes Risk Variants

অনুযায়ী Thomsen, Soren K, Ceroni, Alessandro, van de Bunt, Martijn, Burrows, Carla, Barrett, Amy, Scharfmann, Raphael, Ebner, Daniel, McCarthy, Mark I, Gloyn, Anna L
প্রকাশিত Diabetes (2016)

Patterns of differential gene expression in a cellular model of human islet development, and relationship to type 2 diabetes predisposition

অনুযায়ী Perez-Alcantara, Marta, Honoré, Christian, Wesolowska-Andersen, Agata, Gloyn, Anna L., McCarthy, Mark I., Hansson, Mattias, Beer, Nicola L., van de Bunt, Martijn
প্রকাশিত Diabetologia (2018)

Identification and Functional Characterisation of Novel Glucokinase Mutations Causing Maturity-Onset Diabetes of the Young in Slovakia

অনুযায়ী Valentínová, Lucia, Beer, Nicola L., Staník, Juraj, Tribble, Nicholas D., van de Bunt, Martijn, Hučková, Miroslava, Barrett, Amy, Klimeš, Iwar, Gašperíková, Daniela, Gloyn, Anna L.
প্রকাশিত 2012

Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data

অনুযায়ী Fernández-Tajes, Juan, Gaulton, Kyle J., van de Bunt, Martijn, Torres, Jason, Thurner, Matthias, Mahajan, Anubha, Gloyn, Anna L., Lage, Kasper, McCarthy, Mark I.
প্রকাশিত Genome Med (2019)

Deep learning reveals 3D atherosclerotic plaque distribution and composition

অনুযায়ী Jurtz, Vanessa Isabell, Skovbjerg, Grethe, Salinas, Casper Gravesen, Roostalu, Urmas, Pedersen, Louise, Hecksher-Sørensen, Jacob, Rolin, Bidda, Nyberg, Michael, van de Bunt, Martijn, Ingvorsen, Camilla
প্রকাশিত Sci Rep (2020)

The miRNA Profile of Human Pancreatic Islets and Beta-Cells and Relationship to Type 2 Diabetes Pathogenesis

অনুযায়ী van de Bunt, Martijn, Gaulton, Kyle J., Parts, Leopold, Moran, Ignasi, Johnson, Paul R., Lindgren, Cecilia M., Ferrer, Jorge, Gloyn, Anna L., McCarthy, Mark I.
প্রকাশিত 2013

Colocalization of GWAS and eQTL Signals Detects Target Genes

অনুযায়ী Hormozdiari, Farhad, van de Bunt, Martijn, Segrè, Ayellet V., Li, Xiao, Joo, Jong Wha J., Bilow, Michael, Sul, Jae Hoon, Sankararaman, Sriram, Pasaniuc, Bogdan, Eskin, Eleazar
প্রকাশিত Am J Hum Genet (2016)

Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high-fat diet

অনুযায়ী Kellard, Joely A., Rorsman, Nils J.G., Hill, Thomas G., Armour, Sarah L., van de Bunt, Martijn, Rorsman, Patrik, Knudsen, Jakob G., Briant, Linford J.B.
প্রকাশিত Mol Metab (2020)

Electrophysiological properties of human beta-cell lines EndoC-βH1 and -βH2 conform with human beta-cells

অনুযায়ী Hastoy, Benoît, Godazgar, Mahdieh, Clark, Anne, Nylander, Vibe, Spiliotis, Ioannis, van de Bunt, Martijn, Chibalina, Margarita V., Barrett, Amy, Burrows, Carla, Tarasov, Andrei I., Scharfmann, Raphael, Gloyn, Anna L., Rorsman, Patrik
প্রকাশিত Sci Rep (2018)

PTEN Mutations as a Cause of Constitutive Insulin Sensitivity and Obesity

অনুযায়ী Pal, Aparna, Barber, Thomas M., Van de Bunt, Martijn, Rudge, Simon A., Zhang, Qifeng, Lachlan, Katherine L., Cooper, Nicola S., Linden, Helen, Levy, Jonathan C., Wakelam, Michael J.O., Walker, Lisa, Karpe, Fredrik, Gloyn, Anna L.
প্রকাশিত 2012

Understanding human fetal pancreas development using subpopulation sorting, RNA sequencing and single-cell profiling

অনুযায়ী Ramond, Cyrille, Beydag-Tasöz, Belin Selcen, Azad, Ajuna, van de Bunt, Martijn, Petersen, Maja Borup Kjær, Beer, Nicola L., Glaser, Nicolas, Berthault, Claire, Gloyn, Anna L., Hansson, Mattias, McCarthy, Mark I., Honoré, Christian, Grapin-Botton, Anne, Scharfmann, Raphael
প্রকাশিত Development (2018)

Insights Into the Pathogenicity of Rare Missense GCK Variants From the Identification and Functional Characterization of Compound Heterozygous and Double Mutations Inherited in Cis

অনুযায়ী Beer, Nicola L., Osbak, Kara K., van de Bunt, Martijn, Tribble, Nicholas D., Steele, Anna M., Wensley, Kirsty J., Edghill, Emma L., Colcough, Kevin, Barrett, Amy, Valentínová, Lucia, Rundle, Jana K., Raimondo, Anne, Grimsby, Joseph, Ellard, Sian, Gloyn, Anna L.
প্রকাশিত 2012

Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors

অনুযায়ী van de Bunt, Martijn, Manning Fox, Jocelyn E., Dai, Xiaoqing, Barrett, Amy, Grey, Caleb, Li, Lei, Bennett, Amanda J., Johnson, Paul R., Rajotte, Raymond V., Gaulton, Kyle J., Dermitzakis, Emmanouil T., MacDonald, Patrick E., McCarthy, Mark I., Gloyn, Anna L.
প্রকাশিত PLoS Genet (2015)

Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci

অনুযায়ী Thurner, Matthias, van de Bunt, Martijn, Torres, Jason M, Mahajan, Anubha, Nylander, Vibe, Bennett, Amanda J, Gaulton, Kyle J, Barrett, Amy, Burrows, Carla, Bell, Christopher G, Lowe, Robert, Beck, Stephan, Rakyan, Vardhman K, Gloyn, Anna L, McCarthy, Mark I
প্রকাশিত eLife (2018)