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Patterns of differential gene expression in a cellular model of human islet development, and relationship to type 2 diabetes predisposition
AIMS/HYPOTHESIS: Most type 2 diabetes-associated genetic variants identified via genome-wide association studies (GWASs) appear to act via the pancreatic islet. Observed defects in insulin secretion could result from an impact of these variants on islet development and/or the function of mature isle...
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| 出版年: | Diabetologia |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Berlin Heidelberg
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6354904/ https://ncbi.nlm.nih.gov/pubmed/29675560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-018-4612-4 |
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