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Analysis of Differentiation Protocols Defines a Common Pancreatic Progenitor Molecular Signature and Guides Refinement of Endocrine Differentiation

Several distinct differentiation protocols for deriving pancreatic progenitors (PPs) from human pluripotent stem cells have been described, but it remains to be shown how similar the PPs are across protocols and how well they resemble their in vivo counterparts. Here, we evaluated three differentiat...

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Publicat a:Stem Cell Reports
Autors principals: Wesolowska-Andersen, Agata, Jensen, Rikke Rejnholdt, Alcántara, Marta Pérez, Beer, Nicola L., Duff, Claire, Nylander, Vibe, Gosden, Matthew, Witty, Lorna, Bowden, Rory, McCarthy, Mark I., Hansson, Mattias, Gloyn, Anna L., Honore, Christian
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962645/
https://ncbi.nlm.nih.gov/pubmed/31883919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.11.010
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