Analysis of Differentiation Protocols Defines a Common Pancreatic Progenitor Molecular Signature and Guides Refinement of Endocrine Differentiation

Several distinct differentiation protocols for deriving pancreatic progenitors (PPs) from human pluripotent stem cells have been described, but it remains to be shown how similar the PPs are across protocols and how well they resemble their in vivo counterparts. Here, we evaluated three differentiat...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Wesolowska-Andersen, Agata, Jensen, Rikke Rejnholdt, Alcántara, Marta Pérez, Beer, Nicola L., Duff, Claire, Nylander, Vibe, Gosden, Matthew, Witty, Lorna, Bowden, Rory, McCarthy, Mark I., Hansson, Mattias, Gloyn, Anna L., Honore, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962645/
https://ncbi.nlm.nih.gov/pubmed/31883919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.11.010
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