Insights into islet development and biology through characterization of a human iPSC-derived endocrine pancreas model

Directed differentiation of stem cells offers a scalable solution to the need for human cell models recapitulating islet biology and T2D pathogenesis. We profiled mRNA expression at 6 stages of an induced pluripotent stem cell (iPSC) model of endocrine pancreas development from 2 donors, and charact...

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Detalhes bibliográficos
Publicado no:Islets
Main Authors: van de Bunt, Martijn, Lako, Majlinda, Barrett, Amy, Gloyn, Anna L., Hansson, Mattias, McCarthy, Mark I., Beer, Nicola L., Honoré, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987020/
https://ncbi.nlm.nih.gov/pubmed/27246810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19382014.2016.1182276
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