Genes Associated with Pancreas Development and Function Maintain Open Chromatin in iPSCs Generated from Human Pancreatic Beta Cells

Current in vitro islet differentiation protocols suffer from heterogeneity and low efficiency. Induced pluripotent stem cells (iPSCs) derived from pancreatic beta cells (BiPSCs) preferentially differentiate toward endocrine pancreas-like cells versus those from fibroblasts (FiPSCs). We interrogated...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Stem Cell Reports
Main Authors: Thurner, Matthias, Shenhav, Liraz, Wesolowska-Andersen, Agata, Bennett, Amanda J., Barrett, Amy, Gloyn, Anna L., McCarthy, Mark I., Beer, Nicola L., Efrat, Shimon
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831005/
https://ncbi.nlm.nih.gov/pubmed/29107594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.09.020
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker