Understanding human fetal pancreas development using subpopulation sorting, RNA sequencing and single-cell profiling

To decipher the populations of cells present in the human fetal pancreas and their lineage relationships, we developed strategies to isolate pancreatic progenitors, endocrine progenitors and endocrine cells. Transcriptome analysis of the individual populations revealed a large degree of conservation...

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Dettagli Bibliografici
Pubblicato in:Development
Autori principali: Ramond, Cyrille, Beydag-Tasöz, Belin Selcen, Azad, Ajuna, van de Bunt, Martijn, Petersen, Maja Borup Kjær, Beer, Nicola L., Glaser, Nicolas, Berthault, Claire, Gloyn, Anna L., Hansson, Mattias, McCarthy, Mark I., Honoré, Christian, Grapin-Botton, Anne, Scharfmann, Raphael
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2018
Soggetti:
Human Development
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124547/
https://ncbi.nlm.nih.gov/pubmed/30042179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.165480
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